Think beyond TB lymphadenitis - Kikuchi fujimoto lymphadenitis

---

Case Report

Author Details : Aishwarya Alavandar*, Koushik Muthu Raja Mathivanan

Volume : 9, Issue : 2, Year : 2024

Article Page : 71-74

https://doi.org/10.18231/j.ijirm.2024.014

Suggest article by email

Get Permission

---

Abstract

Kikuchi-Fujimoto disease (KFD) is an extremely unusual lymphadenopathy that typically affects females between the ages of 20 and 40, but the aetiology is still unclear. A 28-year-old female presented with right-sided cervical lymph nodes, but there was no history of fever, anorexia, or loss of appetite. Ultrasonography of the patient's neck revealed bilateral cervical lymphadenopathy. Both the acid-fast bacilli smear and GeneXpert tests returned negative results. Histopathology revealed the presence of lymphocytes and histiocytes mixed with karyorrhectic debris. Immunohistochemistry markers support the diagnosis of Kikuchi-Fujimoto lymphadenitis. This case demonstrates that early recognition of KFD reduces unnecessary evaluations and treatments and patient suffering.
Key messages: KFD is a self-limiting disease that requires a systematic approach for a diagnosis; once the diagnosis is made and confirmed by techniques such as immunohistochemistry, symptomatic treatment alone would suffice in the majority of cases. The commonest presentation is an acute or subacute febrile illness associated with cervical lymphadenopathy.
 

Keywords: Kikuchi­Fujimoto disease, Cervical lymphadenopathy, Tuberculous lymphadenitis

How to cite : Alavandar A, Mathivanan K M R, Think beyond TB lymphadenitis - Kikuchi fujimoto lymphadenitis. IP Indian J Immunol Respir Med 2024;9(2):71-74

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.