Misleading wheeze in a case of atypical large cell neuroendocrine carcinoma of lung - A deadly variety

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Case Report

Author Details : Jeevanandham Anandan*, Zeenathalam Nadaf, Sneha Leo

Volume : 8, Issue : 4, Year : 2023

Article Page : 161-164

https://doi.org/10.18231/j.ijirm.2023.032

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Abstract

Neuroendocrine tumors are neoplasms arising from cells of endocrine and nervous system containing special secretory granules with biogenic amines and polypeptide hormones. One of the varieties that occurs commonly in the lung is large cell neuro endocrine carcinoma. The replicative potential of these neuroendocrine malignancies is so rapid that the patients usually present with metastatic disease. We describe a case of 29-year-old-male presented with nocturnal wheeze which led on to a misdiagnosis of bronchial asthma and finally found to be LCNEC with endobronchial obstruction. They are usually peripherally located lesions, mostly in the upper lung zones of an elderly male smoker. But he had a hilar mass with right lower lobe collapse due to endobronchial obstruction. Hence careful examination of wheeze whether unilateral or bilateral, monophonic or polyphonic, random or fixed, inspiratory or expiratory or biphasic may help in early identification of the endobronchial lesions.

Keywords: LCNEC, Wheeze, Bronchial asthma, Endobronchial lesion

How to cite : Anandan J, Nadaf Z, Leo S, Misleading wheeze in a case of atypical large cell neuroendocrine carcinoma of lung - A deadly variety. IP Indian J Immunol Respir Med 2023;8(4):161-164

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