Clinico-mycological profile of fungal infections in a tertiary care hospital

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Original Article

Author Details : Monica Singh, Veenu Gupta*, Rajesh Mahajan, Jyoti Chaudhary, Manisha Aggarwal

Volume : 8, Issue : 4, Year : 2023

Article Page : 133-139

https://doi.org/10.18231/j.ijirm.2023.027

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Abstract

Background: The fungal infections are increasing at high rate especially in immune-compromised patients and elderly population. In high risk population, antifungal resistance is becoming a major concern. Antifungal susceptibility testing is important for appropriate management and better outcome of patients.
Aim: The aim of the study was to know clinico-Mycological profile of fungal infections in admitted patients.
Materials and Methods: This prospective study was carried out in a tertiary care hospital. Various samples were received from patients with suspected fungal infections. All samples were inoculated on SDA except blood & body fluids which were directly inoculated into blood culture bottles and processed in BACTEK/BacTAlert system. Fungal infections were characterized and antifungal susceptibility was done for yeast isolates with VITEK-AST panel.
Results : Out of total 19698 patients suspected of fungal infection, fungal infection was seen in 365 patients , 100% susceptibility was seen to Fluconazole and Echinocandins. Whereas in NAC (non-albicans ), 72.5% susceptibility was seen to fluconazole and Voriconazole (82.5%).
Conclusion: Antifungal resistance is major cause of morbidity and mortality. Prompt diagnosis and antifungal susceptibility will offer the early appropriate treatment and better clinical outcome of patient.

Keywords: Fungal infections, Antifungal susceptibility, Candidiasis, Aspergillosis

How to cite : Singh M, Gupta V, Mahajan R, Chaudhary J, Aggarwal M, Clinico-mycological profile of fungal infections in a tertiary care hospital. IP Indian J Immunol Respir Med 2023;8(4):133-139

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