Safety and efficacy profile of povidone iodine pleurodesis in patients with spontaneous pneumothorax

Manju M D; Ravikumar P

Safety and efficacy profile of povidone iodine pleurodesis in patients with spontaneous pneumothorax

Original Article

Author Details : Manju M D*, Ravikumar P

Volume : 5, Issue : 1, Year : 2020

Article Page : 4-7

https://doi.org/10.18231/j.ijirm.2020.002

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Abstract

Introduction: Multiple agents are being used for the purpose of chemical pleurodesis with varied success
and risks. Povidone iodine was also a successful agent in inducing pleurodesis in pleural effusions and
pneumothoraces.
Aims and Objectives: To evaluate the efficacy and safety of povidone iodine pleurodesis through
intercostal tube drainage (ICD) in patients with spontaneous pneumothorax.
Materials and Methods: This was a prospective study where povidone iodine was infused into pleural
cavity through ICD in patients with spontaneous pneumothorax. Success of procedure and adverse events
recorded. Patients were followed up for 12 months for recurrence of pneumothorax.
Results: A total of 38 patients with mean age of 58.6 12.5 years were included in study. 28 patients
had successful first procedure, six patients required repeat pleurodesis, three had failed pleurodesis and two
had recurrent pneumothorax after 6 months. All patients experienced chest pain of varying severity. Two
patients had ARDS.
Conclusion: Povidone iodine can be used as effective and safe agent for chemical pleurodesis in
spontaneous pneumothorax.

Keywords: Pleurodesis, Pneumothorax, Povidone iodine, ARDS, Intercostal tube drainage, Talc.

How to cite : Manju M D, Ravikumar P, Safety and efficacy profile of povidone iodine pleurodesis in patients with spontaneous pneumothorax. IP Indian J Immunol Respir Med 2020;5(1):4-7

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