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- DOI 10.18231/j.ijirm.2019.020
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CrossMark
- Citation
Clinical and radiological profile of primary lung malignancies attending tertiary care center
- Author Details:
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Aswani A
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Ramakrishna Rachakonda *
Background: To study the clinical and radiological profile of patients diagnosed to have primary lung cancer in our tertiary care centre.
Methodology: 100 patients diagnosed as primary lung cancer were studied by clinical, radiological, biochemical and histopathological examination.
Results: 82% patients are males and 18% are females. Average age of the patients was 57.6. 82% of them are smokers and 18% are non smokers. Non smoking females gave the history of exposure to passive smoking or biological fuel. All the patients were symptomatic at the time of diagnosis and commonest symptom was cough. Hemoptysis was seen in 22%. History of Pulmonary tuberculosis was seen in 19.5% of males and 11.1% of females. 79% of patients belong to above 51 years of age. 87.82% of patients gave a smoking history of more than 20 pack years. Right lung, upper and middle lobes are commonly involved. 68% of patients presented with mass lesions. Predominant symptom was cough present in all patients followed by shortness of breath and chest pain. Mass and intrathoracic lymphadenopathy were common presentation. 74% patients presented with contralateral hilar. Sub-carinal, contralateral mediastinal or supraclavicular lymphadenopathy suggesting inoperability. Single or multiple site extra-pulmonary metastasis was seen in liver, bone, brain and adrenals.
Conclusions: Primary lung cancer is a disease of 6th decade. Smoking is a significant causative factor. Most of the patients presented in inoperable state. Measures to discourage smoking habits among youth can prevent the dreadful disease to some extent.
Keywords: Primary lung cancer; Hemoptysis; Mass lesion; Lymphadenopathy; Metastasis.
References
- Charles S. Dela Cruz. Lung Cancer: Epidemiology, Etiology, and Prevention. Clin Chest Med 2011;32(4):10.
- Bruceet N. Does household use of biomass fuel cause lung cancer? A systematic review and evaluation of the evidence for the GBD 2010 study. Thorax 2015;0:1–9.
- Alberget AJ. Epidemiology of Lung Cancer, Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines, Chest 2013;143(5):e1S–e29S.
- Gadgeel SM. Lung Cancer in Patients < 50 Years of Age. Chest 1999;115(5):1232–6.
- Noronha V, Dikshit R, Raut N, Joshi A, Pramesh CS, George K, et al. Epidemiology of lung cancer in India: Focus on the differences between non-smokers and smokers: A single-centre experience. Indian J Cancer 2012;49:74-81.
- Behera D. Epidemiology of lung cancer – Global and Indian perspective. JIACM 2012;13(2):131-7.
- Brown JS, Eraut D, Trask C, Davison AG. Age and the treatment of lung cancer, Thorax 1996;51(6): 564–8.
- Noronha V, Pinninti R, Patil VM, Joshi A, Kumar P, Lung cancer in the Indian subcontinent, South Asian J Cancer 2016;5(3):95–103.
- Patricia M. de Groot, Carol C. Wu,1 Brett W. Carter, Reginald F. Munden, The epidemiology of lung cancer, Transl Lung Cancer Res 2018;7(3):220–33.
- Behera D. Lung Cancer in India. Medicine Update. 2012;22:5.
- J Corner, J Hopkinson, D Fitzsimmons, S Barclay, M Muers, Is late diagnosis of lung cancer inevitable? Interview study of patients’ recollections of symptoms before diagnosis. Thorax 2005;60:314–9.
- Sharma CP. Radiographic Patterns in Lung Cancer. Indian J Chest Dis Allied Sci 2002;44:25-301.
- Janjigian YY, McDonnell K, Kris MG, Shen R, Sima CS, Peter B, et al. Pack Years of Cigarette Smoking as a Prognostic Factor in Patients with Stage IIIB/IV Non-Small Cell Lung Cancer, Cancer 2010;116(3):670–5.
- Dey A, Biswas D, Saha S K, Kundu S, Kundu S, Sengupta A. Comparison study of clinicoradiological profile of primary lung cancer cases: An Eastern India experience. Indian J Cancer 2012;49:89-95.
- DiPerna CA, Wood DE. Surgical Management of T3 and T4 Lung Cancer. Clin Cancer Res 2005;11(13):12.
- Alex MR. Prognostic classifications of lymph node involvement in lung cancer and current International Association for the Study of Lung Cancer descriptive classification in zones. Interactive Cardio Vascular Thoracic Surg 2010;11(3):16.
- Riihimäki M. Metastatic sites and survival in lung cancer. Lung Cancer 2014;86(1):78-84.
How to Cite This Article
Vancouver
A A, Rachakonda R. Clinical and radiological profile of primary lung malignancies attending tertiary care center [Internet]. IP Indian J Immunol Respir Med. 2019 [cited 2025 Oct 16];4(2):86-89. Available from: https://doi.org/10.18231/j.ijirm.2019.020
APA
A, A., Rachakonda, R. (2019). Clinical and radiological profile of primary lung malignancies attending tertiary care center. IP Indian J Immunol Respir Med, 4(2), 86-89. https://doi.org/10.18231/j.ijirm.2019.020
MLA
A, Aswani, Rachakonda, Ramakrishna. "Clinical and radiological profile of primary lung malignancies attending tertiary care center." IP Indian J Immunol Respir Med, vol. 4, no. 2, 2019, pp. 86-89. https://doi.org/10.18231/j.ijirm.2019.020
Chicago
A, A., Rachakonda, R.. "Clinical and radiological profile of primary lung malignancies attending tertiary care center." IP Indian J Immunol Respir Med 4, no. 2 (2019): 86-89. https://doi.org/10.18231/j.ijirm.2019.020